Romano M., Squeglia F., Kramarska E., Barra G., Choi H.G., Kim H.J., Ruggiero A., Berisio R. “A Structural View at Vaccine Development against M. tuberculosis” Cells. 2023 Jan 14;12(2):317. doi: 10.3390/cells12020317.
Squeglia F.*, Romano M.,* Esposito L., Barra G., Campiglia P., Sala M., Scala M.C., Ruggiero A., Berisio R. “Structure-Based Development of SARS-CoV-2 Spike Interactors” Int J Mol Sci. 2022 May 17;23(10):5601. doi: 10.3390/ijms23105601. (*equally contributed).
Squeglia F.,* Romano M.*, Ruggiero A., Maga G., Berisio R. “Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins” Front Chem 2020 doi: 10.3389/fchem.2020.602162 (equally contributed).
Dennehy, Duggan N., Dignam S., McCormack S., Dillon E., Molony J., Romano M., Hou Y., Ardill L., Whelan M.V.X., Drulis-Kawa Z., Ó'Cróinín T., Valvano M.A., Berisio R., McClean S. “Protein with negative surface charge distribution, Bnr1, shows characteristics of a DNA-mimic protein and may be involved in the adaptation of Burkholderia cenocepacia” Microbiologyopen. 2022 Feb;11(1):e1264. doi: 10.1002/mbo3.1264.
Omari K. E., Mohamad N., Bountra K., Duman R., Romano M., Schlegel K., Kwong H.S., Mykhaylyk V., Olesen C., Moller J. V. , Bublitz M., Beis K. and Wagner A. “Experimental phasing with vanadium and application to nucleotide-binding proteins” IUCrJ 2020. doi: https://doi.org/10.1107/S2052252520012312
Dennehy R., Dignam S., McCormack S., Romano M., Hou Y., Ardill L., Whelan MX., Drulis-Kawa Z., Cróinín Ó.T., Valvano M.A., Berisio R., McClean S. “The DNA mimic protein BCAS0292 is involved in the regulation of virulence of Burkholderia cenocepacia” Pre-print on BioRxiv 2020 doi: 10.1101/2020.08.06.226779
Squeglia F., Romano M., Ruggiero A., Maga G., Berisio R. “Host DDX Helicases as Possible SARS-CoV-2 Proviral Factors: A Structural Overview of Their Hijacking Through Multiple Viral Proteins” Front Chem. Dec 2020 doi: 10.3389/fchem.2020.602162 (review)
Romano M., Ruggiero A., Squeglia F., Berisio R. “An engineered stable miniprotein to plug SARS-CoV-2 Spikes” Pre-print on BioRxiv 2020 doi: 10.1101/2020.04.29.067728
Romano M., Ruggiero A., Squeglia F., Maga G. and Berisio R. “A Structural View of SARS-CoV-2 RNA Replication Machinery: RNA Synthesis, Proofreading and Final Capping” Cells 2020, 9, 1267. doi: 10.3390/cells9051267. (review)
Omari K.E., Mohamad N., Bountra K., Duman R., Romano M., Schlegel K., Knong H.S., Mykhaylyk V., Olesen C., Moller J.V., Bublitz M., Beis K. and Wagner A. "Experimental phasing with vanadium and application to nucleotide-binding membrane proteins". IUCRJ, Nov 2020 - ISSN: 2052-2525, doi: 10.1107/S2052252520012312
Wong J., Romano M., Kerry L., Kwong H., Low W., Brett S., Clements A., Beis K., Frankel G. “OmpK36-mediated Carbapenem resistance attenuates ST258 Klebsiella pneumoniae in vivo” Nat Commun. 2019 Sep 2;10(1):3957. doi: 10.1038/s41467-019-11756-y.
Calvanese L., Squeglia F., Romano M., D'Auria G., Falcigno L., Berisio R. “Structural and dynamic studies provide insights into specificity and allosteric regulation of ribonuclease AS, a key enzyme in mycobacteria virulence" J Biomol Struct Dyn. 2019 Jul 22:1-13. doi: 10.1080/07391102.2019.1643786
Wang L., Bateman B., Zanetti-Domingues L.C., Moores AN., Astbury S., Spindloe C., Darrow MC., Romano M., Needham SR., Beis K., Rolfe DJ., Clarke DT., Martin-Fernandez ML. “Solid immersion microscopy images cells under cryogenic conditions with 12nm resolution” Commun. Biol. 2019 Feb 21;2:74. doi: 10.1038/s42003-019-0317-6. eCollection 2019.
Husada F., Bountra K., Tassis K., de Boer M., Romano M., Rebuffat S., Beis K., Cordes T. “Conformational dynamics of the ABC transporter McjD seen by single-molecule FRET” EMBO J. 2018 Nov 2;37(21). pii: e100056. doi: 10.15252/embj.2018100056. Epub 2018 Sep 20.
Romano M., Fusco G., Choudhury H.G., Mehmood S., Robinson C.V., Zirah S., Hegemann J.D., Lescop E., Marahiel M.A., Rebuffat S., De Simone A., Beis K. “Structural Basis for Natural Product Selection and Export by Bacterial ABC Transporters” ACS Chem Biol. 2018 Jun 15;13(6):1598-1609. doi: 10.1021/acschembio.8b00226. Epub 2018 May 18.
Squeglia F., Romano M., Ruggiero A., Berisio R. “Molecular Players in Tuberculosis Drug Development: Another Break in the Cell Wall” Curr Med Chem. 2017 Nov 24;24(36):3954-3969. doi: 10.2174/0929867324666170208150016. (review)
Majkowska-Skrobek G., Łątka A., Berisio R., Maciejewska B., Squeglia F., Romano M., Lavigne R., Struve C., Drulis-Kawa Z. “Capsule-Targeting Depolymerase, Derived from Klebsiella KP36 Phage, as a Tool for the Development of Anti-Virulent Strategy” Viruses. 2016 Dec 1;8(12). pii: E324. doi:10.3390/v8120324
Dennehy R, Romano M, Ruggiero A, Mohamed YF, Dignam SL, Mujica Troncoso C, Callaghan M, Valvano MA, Berisio R, McClean S. “The Burkholderia cenocepacia peptidoglycan-associated lipoprotein is involved in epithelial cell attachment and elicitation of inflammation” Cell Microbiol. 2017 May;19(5). doi: 10.1111/cmi.12691. Epub 2016 Nov 25.
Ruggiero A, Squeglia F, Romano M, Vitagliano L, De Simone A, Berisio R. “Structure and dynamics of the multi-domain resuscitation promoting factor RpfB from Mycobacterium tuberculosis” J Biomol Struct Dyn. 2017 May;35(6):1322-1330. doi: 10.1080/07391102.2016.1182947. Epub 2016 Jul 15.
Ruggiero A, Squeglia F, Romano M, Berisio R. “Use of Hydrolytic Enzymes for Algal Biomass Treatment” Current Biotechnology Volume 5, Issue 4, 2016 doi: 10.2174/2211550105666160518143432 (review)
Casey W., Spink N., Cia F., Collins C., Romano M., Berisio R., Gregory J. Bancroft & McClean S. “Identification of an OmpW homologue in Burkholderia pseudomallei, a protective vaccine antigen against melioidosis”, Vaccine. 2016. doi:10.1016/j.vaccine.2016.03.088
Ruggiero A., Squeglia F., Romano M., Vitagliano L., De Simone A., Berisio R. “The structure of Resuscitation promoting factor B from M. tuberculosis reveals unexpected ubiquitin-like domains”, Biochim Biophys Acta. 2016 Feb;1860(2):445-51. doi:10.1016/j.bbagen.2015.11.001 Epub 2015 Nov 5.
Romano M., Squeglia F., Berisio R. “Structure and function of RNase AS: A novel virulence factor from mycobacterium tuberculosis”, Curr Med Chem. 2015;22(14):1745-56. doi: 10.2174/0929867322666150417125301 (review)
Squeglia F., Ruggiero A., Romano M., Vitagliano L. and Berisio R. “Mutational and structural study of RipA, a key enzyme for Mycobacterium tuberculosis cell division: evidence for the L- to D-inversion of configuration of the catalytic cysteine”, Acta Crystallogr D Biol Crystallogr. 2014 Sep;70(Pt 9):2295-300. doi:10.1107/S1399004714013674 Epub 2014 Aug 29.
Romano M., van de Weerd R., Brouwer F.C.C., Roviello G., Lacroix R., Vandenbroucke-Grauls C.M.J.E, Sparrius M., Brink-van Stempvoort G., Maaskant J.J., van der Sar A.M., Appelmelk B.J., Geurtsen J.J., Berisio R. “Structure and function of RNase AS, a polyadenylate-specific exoribonuclease affecting mycobacterial virulence in vivo” - Structure. 2014 May 6;22(5):719-30. doi:10.1016/j.str.2014.01.014. Epub 2014 Apr 3.
Squeglia F., Bachert B., Romano M., Lukomski S., Berisio R. “Crystallization and preliminary X-ray crystallographic analysis of the variable domain of Scl2.3, a streptococcal collagen-like protein from invasive M3-type Streptococcus pyogenes”, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Sep;69(Pt 9):1023-5. doi: 10.1107/S174430911302068X
Squeglia F, Romano M, Ruggiero A, Vitagliano L, De Simone A, Berisio R. “Carbohydrate Recognition by RpfB from Mycobacterium tuberculosis Unveiled by Crystallographic and Molecular Dynamics Analyses”, Biophys J., 2013 Jun 4;104(11):2530-9. doi:10.1016/j.bpj.2013.04.040
